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Lysofix™ Liquid

Emulsifiers

Gentle and effective silky cold process emulsifier for skin and hair

Lysofix™ Liquid is a natural emulsifier made of lysophospholipids, allowing it to create thin and stable O/W emulsions with micellar structure composed of small droplets. It has a versatile profile for wide textures possibilities to create luxurious, high-performance formulas for skin and hair.

Ease of formulation

Lysofix™ Liquid is easy to use in formulations due to its:

  • high compatibility with a broad spectrum of ingredients
  • powerful emulsifying properties (up to 60% oil phase)
  • wide range of pH (4 to 8)

It allows to create an extensive range of O/W textures and applications
(from sprayable to creams)

For color cosmetics and suncare, Lysofix™ Liquid:

  • delivers optimal particles dispersion
  • offers superior color homogeneity and intensity.

It brings a premium skin feel:

  • exceptional spreadability on the skin

  • silky and elegant after feel

  • luxurious and non-tacky skin feel

 

Skin care benefits

Skin enhancer

Lysofix™ Liquid provides immediate hydration and keeps the skin moisturized for at least 4 hours after application.

Helps restructure the skin:

  • supports Pro-collagen I synthesis (+25%) to restore skin bounce
  • increases Tropoelastin production (+58%) for a more youthful look

Ideal for sensitive skin: 

  • delivers powerful anti-inflammatory action (-33% IL-8)
  • visibly reduces redness (-26% erythema after 2 hours)

 

Bar graph showing erythema index variation in skin redness over 1 and 2 hours for untreated, placebo, and Lysolecithin 0.5% treatments, with Lysolecithin reducing redness significantly.

Support active formulas efficacy

 Lysofix™ Liquid boosts active ingredient bioavailablity for enhanced efficacy at lower dosage: by modifying the fluidity of the stratum corneum, Lysofix™ Liquid improves the bioavailability of both lipophilic and hydrophilic active ingredients and increases their penetration into deeper skin layers, maximizing product effectiveness.

Tested with:

  • lipophilic active ingredients (such as CoQ10) 
  • hydrophilic active ingredients (such as caffeine and beta-arbutin)

The graph shows the diffusion of CoQ₁₀ during 24 hours, measured as the amount of CoQ₁₀ delivered (DPM) over time (hours). Key observations: - The pink line represents "1% Lysofilx™ Liquid + 0.5% CoQ₁₀ in PBS Buffer." This condition shows a steady increase in CoQ₁₀ delivery over time, reaching around 525 DPM at 24 hours. - The black line represents the "Positive control: 60% DMSO + 0.5% CoQ₁₀ in PBS Buffer." This condition shows an initial increase, peaking around 6 hours at approximately 290 DPM, then fluctuates and stabilizes around 190-210 DPM for the remainder of the 24 hours. - The gray line represents the "Negative control: 0.5% CoQ₁₀ in PBS Buffer." This condition shows a slow increase, reaching about 130 DPM at 24 hours. Summary: - The 1% Lysofilx™ Liquid formulation significantly enhances the diffusion of CoQ₁₀ compared to both positive and negative controls. - The positive control shows moderate diffusion initially but plateaus early. - The negative control shows the least diffusion over 24 hours.

Hair care performance

Hair fortifier

Lysofix™ Liquid enhances hair shaft vitality by stimulating multiplication of Hair Follicle Dermal Papilla Cells (HFDPC) and reinforcing hair structure:

  • x3 Ki67 (marker of dividing cells)
  • +22% hair follicle length
  • x9 keratin-40 expression
  • x3 keratin-71 expression 
The image shows two panels comparing untreated and Lysofix™ Liquid treated samples stained with DAPI (blue) and Ki67 (green). - The untreated sample (left) shows very few green Ki67-positive cells, indicated by white arrows, suggesting low cell proliferation. - The Lysofix™ Liquid treated sample (right) shows a significantly higher number of green Ki67-positive cells, also indicated by white arrows, suggesting increased cell proliferation. The scale bar in the Lysofix™ Liquid panel indicates 100 µm for size reference. The insets provide a zoomed-in view of the respective samples, highlighting the difference in Ki67 expression more clearly. Overall, the treatment with Lysofix™ Liquid appears to enhance cell proliferation compared to the untreated condition.

Restructured and healthier hair

0.5% Lysofix™ Liquid  fortifies hair and restores hair fiber integrity for healthier looking hair:

  • increases hair structural integrity (+11.5%)
  • decreases hair porosity (-21%)
  • increases hair smoothness for effortless combing (rinse-off)
Comparison of hair shaft images showing +11.5% improved hair integrity with Lysofix Liquid versus placebo, and reductions in wet combing force by 17% and dry combing force by 38%.

Conscious sourcing

Lysofix™ Liquid is obtained from certified lecithins, guaranteing non-GMO and zero deforestation and valorizing an industrial by-product of the food industry into a premium cosmetic ingredient.

  • 100% Natural Origin content
  • Readily biodegradable

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